7-溴靛红(cas号:20780-74-9)

中文名称:7-溴靛红

中文别名:7-溴吲哚-2,3-二酮;7-溴-1H-吲哚-2,3-二酮;7-溴吲哚-1H-2,3-二酮;7-溴-2,3-二氧代吲哚啉;7-溴吲哚满二酮;

英文名称:7-Bromoisatin

CAS号:20780-74-9

性状:深红色粉末

含量:≥98%

分子式:C8H4BrNO2

分子量:226.0269

精确质量:224.94300

密度:1.826g/cm3 

熔点:199℃

折射率:1.649

PSA:46.17000
logP:1.72190

产品包装:25kg纸板桶

储存条件:干燥密封

检测方法:核磁 液相

合成路线:

(2E)-n-(2-溴苯基)-2-(羟基亚氨基)乙酰胺(cas号:101080-38-0)→7-溴靛红(cas号:20780-74-9)

(S,E)-tert-butyl 4-((7-bromo-2-oxoindolin-3-ylidene)methyl)-2,2-dimethyloxazolidine-3-carboxylate(cas号:320734-34-7)→7-溴靛红(cas号:20780-74-9)+tert-butyl (R)-4-((R)-((S)-7-bromo-3-hydroxy-2-oxoindolin-3-yl)(hydroxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate(cas号:320734-37-0)

2-溴苯胺(cas号:615-36-1)→7-溴靛红(cas号:20780-74-9)

水合氯醛(cas号:302-17-0)+2-溴苯胺(cas号:615-36-1)→7-溴靛红(cas号:20780-74-9)

三氯乙醛(cas号:75-87-6)+2-溴苯胺(cas号:615-36-1)→7-溴靛红(cas号:20780-74-9)

tert-butyl (S,Z)-4-((7-bromo-2-oxoindolin-3-ylidene)methyl)-2,2-dimethyloxazolidine-3-carboxylate(cas号:320734-36-9)→7-溴靛红(cas号:20780-74-9)

N-(2-bromophenyl)-2,2,2-trichloroacetamide(cas号:349637-17-8)→7-溴靛红(cas号:20780-74-9)

oxalic acid bis(2-bromoanilide)(cas号:60170-00-5)→7-溴靛红(cas号:20780-74-9)

上游原料:

(S,E)-tert-butyl 4-((7-bromo-2-oxoindolin-3-ylidene)methyl)-2,2-dimethyloxazolidine-3-carboxylate(cas号:320734-34-7)

oxalic acid bis(2-bromoanilide)(cas号:60170-00-5)

N-(2-bromophenyl)-2,2,2-trichloroacetamide(cas号:349637-17-8)

tert-butyl (S,Z)-4-((7-bromo-2-oxoindolin-3-ylidene)methyl)-2,2-dimethyloxazolidine-3-carboxylate(cas号:320734-36-9)

(2E)-n-(2-溴苯基)-2-(羟基亚氨基)乙酰胺(cas号:101080-38-0)

三氯乙醛(cas号:75-87-6)

2-溴苯胺(cas号:615-36-1)

水合氯醛(cas号:302-17-0)

下游产品:

tert-butyl (R)-4-((R)-((S)-7-bromo-3-hydroxy-2-oxoindolin-3-yl)(hydroxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate(cas号:320734-37-0)